Title : Aberrant redox regulation in human metastatic melanoma cells compared to normal melanocytes.

Pub. Date : 2001 Sep 15

PMID : 11557318






2 Functional Relationships(s)
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1 Additionally, recruitment of AP-1 binding in melanoma cells was directly correlated with intracellular levels of superoxide anion (but not hydrogen peroxide). Superoxides JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 The responsiveness of NF-kappaB and AP-1 recruitment to intracellular levels of hydrogen peroxide and superoxide anion without concomitant control of apoptosis provides a general mechanism by which these cells can escape noxious injury (e.g., chemotherapy). Superoxides JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens