Title : Plant stanol fatty acid esters inhibit cholesterol absorption and hepatic hydroxymethyl glutaryl coenzyme A reductase activity to reduce plasma levels in rabbits.

Pub. Date : 2001 Sep

PMID : 11555847






1 Functional Relationships(s)
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1 Hepatic hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase activity reflecting cholesterol synthesis and low-density lipoprotein receptor-mediated binding unexpectedly decreased 67% (P <.01) and 57% (P <.05) in rabbits fed 1.2% SE alone. Cholesterol 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oryctolagus cuniculus