Pub. Date : 2001 Nov 16
PMID : 11551901
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This conclusion is based on observations indicating that cyclin D1 induction by transforming Ha-Ras was depressed in a dose-dependent manner by PD98059, a selective inhibitor of the mitogen-activated kinase kinase MEK-1, demonstrating that Ha-Ras employs extracellular signal-regulated kinases (ERKs) for signal transmission to the cyclin D1 promoter. | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | cyclin D1 | Homo sapiens |
| 2 | This conclusion is based on observations indicating that cyclin D1 induction by transforming Ha-Ras was depressed in a dose-dependent manner by PD98059, a selective inhibitor of the mitogen-activated kinase kinase MEK-1, demonstrating that Ha-Ras employs extracellular signal-regulated kinases (ERKs) for signal transmission to the cyclin D1 promoter. | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | cyclin D1 | Homo sapiens |