Title : Pharmacological similarities and differences between beta2-agonists.

Pub. Date : 2001 Aug

PMID : 11534896






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Adequate water solubility and moderate lipophilicity of formoterol ensures rapid diffusion to the beta2-receptor on the smooth muscle and rapid bronchodilating activity. Formoterol Fumarate potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens
2 Unlike salbutamol, which is hydrophilic and has a rapid onset and short duration of action, both formoterol and salmeterol possess adequate lipophilic properties to remain in the airway tissues as a depot in close vicinity to the beta2-receptor, explaining their long duration of effect. Formoterol Fumarate potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens