Title : HIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levels.

Pub. Date : 2001

PMID : 11532197






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Overexpression of HIPK2 leads to an increase of p53 protein expression or stability, which becomes enhanced further in the presence of the DNA damaging drug doxorubicin. Doxorubicin homeodomain interacting protein kinase 2 Homo sapiens