Title : Low-molecular-weight heparin prevents high glucose- and phorbol ester-induced TGF-beta 1 gene activation.

Pub. Date : 2001 Sep

PMID : 11532088






2 Functional Relationships(s)
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1 The effect of LMW heparin on the binding of nuclear proteins to a regulatory activator protein-1 (AP-1) site, which mediates the high glucose and PMA responsiveness of the TGF-beta 1 promoter, was studied by electrophoretic mobility shift assays. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens
2 The effect of LMW heparin on the binding of nuclear proteins to a regulatory activator protein-1 (AP-1) site, which mediates the high glucose and PMA responsiveness of the TGF-beta 1 promoter, was studied by electrophoretic mobility shift assays. Tetradecanoylphorbol Acetate JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens