Pub. Date : 2000 Nov
PMID : 11514953
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The purpose of this study is to explain the protective effects of physostigmine against paraoxon toxicity by suppressing CYP3A, and hence, decreasing formation of a toxic metabolite, paraoxon. | Physostigmine | cytochrome P450, family 3, subfamily a, polypeptide 62 | Rattus norvegicus |
| 2 | The above data suggested that the formation of paraoxon was inhibited in rats pretreated with physostigmine by inhibiting CYP3A. | Physostigmine | cytochrome P450, family 3, subfamily a, polypeptide 62 | Rattus norvegicus |