Title : A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line.

Pub. Date : 2001 Oct 19

PMID : 11514566






1 Functional Relationships(s)
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1 In this report, we demonstrate that indomethacin and sulindac sulfide induce apoptosis of human leukemic Jurkat cells by a mechanism that requires the Fas-associated Death Domain Protein-mediated activation of a caspase-8-dependent pathway. Indomethacin Fas associated via death domain Homo sapiens