Title : Targeting tumor cell resistance to apoptosis induction with antisense oligonucleotides: progress and therapeutic potential.

Pub. Date : 2001 Feb

PMID : 11512155






1 Functional Relationships(s)
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1 Recently developed antisense oligonucleotides with the ability to inhibit the expression of anti-apoptotic proteins, including Bcl-2, Bcl-xL, FLIP and surviving, have been shown to facilitate tumor cell apoptosis and sensitize tumor cells to cytotoxic treatments. Oligonucleotides BCL2 like 1 Homo sapiens