Title : Liposomal and nonliposomal drug pharmacokinetics after administration of liposome-encapsulated vincristine and their contribution to drug tissue distribution properties.

Pub. Date : 2001 Sep

PMID : 11504822






2 Functional Relationships(s)
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1 Vincristine elimination from the circulation after injection of conventional, aqueous formulated vincristine (C-VINC) was characterized by a short half-life (1.36 h), low plasma area under the plasma concentration-time curve (AUC) (0.59 microg x h/ml), and large volume of distribution (145 ml). Vincristine nuclear paraspeckle assembly transcript 1 (non-protein coding) Mus musculus
2 Vincristine elimination from the circulation after injection of conventional, aqueous formulated vincristine (C-VINC) was characterized by a short half-life (1.36 h), low plasma area under the plasma concentration-time curve (AUC) (0.59 microg x h/ml), and large volume of distribution (145 ml). Vincristine nuclear paraspeckle assembly transcript 1 (non-protein coding) Mus musculus