Title : Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin.

Pub. Date : 2001 Aug

PMID : 11503007






1 Functional Relationships(s)
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1 The aim of this study was to investigate modulation of the CYP-mediated metabolism of ifosfamide with ketoconazole, a potent inhibitor of CYP3A4, and rifampin (INN, rifampicin), an inducer of CYP3A4/CYP2B6. Rifampin cytochrome P450 family 2 subfamily B member 6 Homo sapiens