Title : Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicin-treated human breast carcinoma cells.

Pub. Date : 2001 Sep

PMID : 11502879






1 Functional Relationships(s)
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1 Interestingly, in addition to a decrease in ROS production, the activation of neutral sphingomyelinase, sphingomyelin hydrolysis, and ceramide generation in response to doxorubicin was impaired in T47D/GPx2 cells compared with control cells. Ceramides glutathione peroxidase 2 Homo sapiens