Title : p53 Protects renal inner medullary cells from hypertonic stress by restricting DNA replication.

Pub. Date : 2001 Sep

PMID : 11502601






1 Functional Relationships(s)
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1 Caffeine (2 mM) greatly reduces the p53 level and Ser(15) phosphorylation, followed by a remarkable increase of DNA replication rate, by failure of hypertonicity to inhibit it, and by reduction of cell number during hypertonicity. Caffeine transformation related protein 53, pseudogene Mus musculus