Pub. Date : 2001 Sep
PMID : 11502571
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Depletion of cellular polyamines by treatment with alpha-difluoromethylornithine (DFMO) increased p53 gene expression and caused growth inhibition in the intact small intestinal mucosa and the cultured cells. | Eflornithine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 2 | Depletion of cellular polyamines by treatment with alpha-difluoromethylornithine (DFMO) increased p53 gene expression and caused growth inhibition in the intact small intestinal mucosa and the cultured cells. | Eflornithine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 3 | Induction of p53 mRNA levels in DFMO-treated cells was paralleled by an increase in the rate of newly synthesized p53 protein. | Eflornithine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 4 | Induction of p53 mRNA levels in DFMO-treated cells was paralleled by an increase in the rate of newly synthesized p53 protein. | Eflornithine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 5 | Inhibition of the p53 gene expression by using p53 antisense oligodeoxyribonucleotides significantly promoted cell growth in the presence of DFMO. | Eflornithine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 6 | Inhibition of the p53 gene expression by using p53 antisense oligodeoxyribonucleotides significantly promoted cell growth in the presence of DFMO. | Eflornithine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |