Title : ABO/Secretor genetic complex and susceptibility to asthma in childhood.

Pub. Date : 2001 Jun

PMID : 11491170






1 Functional Relationships(s)
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1 Since the oligosaccharide composition of cell membrane and mucosal secretions is controlled by the cooperative interaction of ABO and Secretor genes, and since such composition influences the adhesion of infectious agents, the age pattern could reflect a more general interaction between developmental maturation and oligosaccharide structure concerning their effects on susceptibility to viral and bacterial agents. Oligosaccharides ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Homo sapiens