Title : Vasopressin induced cyclooxygenase dependent superoxide generation contributes to K(+) channel function impairment after brain injury.

Pub. Date : 2001 Aug 10

PMID : 11489250






4 Functional Relationships(s)
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1 Vasopressin induced cyclooxygenase dependent superoxide generation contributes to K(+) channel function impairment after brain injury. Superoxides vasopressin Sus scrofa
2 This study determined if vasopressin generates superoxide anion (O2(-)) in a cyclooxygenase dependent manner and if such production contributes to impairment of dilation to activators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid percussion brain injury (FPI) in newborn pigs equipped with closed cranial windows. Superoxides vasopressin Sus scrofa
3 This study determined if vasopressin generates superoxide anion (O2(-)) in a cyclooxygenase dependent manner and if such production contributes to impairment of dilation to activators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid percussion brain injury (FPI) in newborn pigs equipped with closed cranial windows. Superoxides vasopressin Sus scrofa
4 These data show that vasopressin increased O2(-) production in a cyclooxygenase dependent manner and contributed to this production after FPI. Superoxides vasopressin Sus scrofa