Title : Insulin receptor substrate-2 phosphorylation is necessary for protein kinase C zeta activation by insulin in L6hIR cells.

Pub. Date : 2001 Oct 5

PMID : 11481324






1 Functional Relationships(s)
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1 Inhibition of PKC zeta activity, however, reduced Akt/PKB phosphorylation of the key serine sites on GSK3 alpha and -beta by >80% (p < 0.001) and prevented full GSK3 inactivation by insulin. Serine v-akt murine thymoma viral oncogene homolog 1 S homeolog Xenopus laevis