Pub. Date : 2001 Aug
PMID : 11479630
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | A cancer cell line selected for resistance to Et743 had chromosome alterations in a region that included the gene implicated in the hereditary disease xeroderma pigmentosum (XPG, also known as Ercc5). | Trabectedin | ERCC excision repair 5, endonuclease | Homo sapiens | ||
2 | A cancer cell line selected for resistance to Et743 had chromosome alterations in a region that included the gene implicated in the hereditary disease xeroderma pigmentosum (XPG, also known as Ercc5). | Trabectedin | ERCC excision repair 5, endonuclease | Homo sapiens | ||
3 | Xeroderma pigmentosum cells deficient in the NER genes XPG, XPA, XPD or XPF were resistant to Et743, and sensitivity was restored by complementation with wild-type genes. | Trabectedin | ERCC excision repair 5, endonuclease | Homo sapiens |