Title : Propofol increases myofilament Ca2+ sensitivity and intracellular pH via activation of Na+-H+ exchange in rat ventricular myocytes.

Pub. Date : 2001 Jun

PMID : 11465603






2 Functional Relationships(s)
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1 Increasing pHi (7.05 +/- 0.03 to 7.39 +/- 0.04) with NH4Cl increased myocyte shortening by 35 +/- 12%. Ammonium Chloride glucose-6-phosphate isomerase Rattus norvegicus
2 Washout of NH4Cl decreased pHi to 6.82 +/- 0.03 and decreased myocyte shortening to 52 +/- 10% of control. Ammonium Chloride glucose-6-phosphate isomerase Rattus norvegicus