Pub. Date : 2000 Sep
PMID : 11465082
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human FMO3 N-oxygenates primary, secondary and tertiary amines whereas human FMO1 is only highly efficient at N-oxygenating tertiary amines. | Amines | flavin containing dimethylaniline monoxygenase 3 | Homo sapiens |
| 2 | Human FMO3 N-oxygenates primary, secondary and tertiary amines whereas human FMO1 is only highly efficient at N-oxygenating tertiary amines. | Amines | flavin containing dimethylaniline monoxygenase 3 | Homo sapiens |
| 3 | Human FMO3 is sensitive to steric features of the substrate and aliphatic amines with linkages between the nitrogen atom and a large aromatic group such as a phenothiazine of at least five carbons are N-oxygenated significantly more efficiently than those substrates with two or three carbons. | Amines | flavin containing dimethylaniline monoxygenase 3 | Homo sapiens |
| 4 | For amines with smaller aromatic substituents such as phenethylamines, often these compounds are efficiently N-oxygenated by human FMO3. | Amines | flavin containing dimethylaniline monoxygenase 3 | Homo sapiens |