Pub. Date : 2001 Jun
PMID : 11457660
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It has been shown recently that androstenol and androstanol could modulate gene expression through the nuclear orphan receptors CAR (constitutive androstane receptor) and PXR (pregnane X receptor). | Androstenols | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
| 2 | It has been shown recently that androstenol and androstanol could modulate gene expression through the nuclear orphan receptors CAR (constitutive androstane receptor) and PXR (pregnane X receptor). | Androstenols | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
| 3 | It has also been shown recently that androstenol could modulate the activity of CAR and PXR and the expression of some cytochrome P450 drug-metabolizing enzymes. | Androstenols | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |
| 4 | We thus provided evidence that androstenol, the ligand for CAR and PXR, is produced by the biosynthetic pathway of sex steroids. | Androstenols | nuclear receptor subfamily 1 group I member 3 | Homo sapiens |