Title : Acute actions of tumor necrosis factor-alpha on intracellular Ca(2+) and K(+) currents in human microglia.

Pub. Date : 2001

PMID : 11457600






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TNFalpha elicited a linear increase in [Ca(2+)]i to a plateau level in microglia bathed in either standard physiological saline solution or Ca(2+)-free physiological saline solution. Sodium Chloride tumor necrosis factor Homo sapiens
2 TNFalpha elicited a linear increase in [Ca(2+)]i to a plateau level in microglia bathed in either standard physiological saline solution or Ca(2+)-free physiological saline solution. Sodium Chloride tumor necrosis factor Homo sapiens
3 The rate of increase of [Ca(2+)]i induced by TNFalpha in Ca(2+)-free physiological saline solution was not altered by prior application of ATP to deplete inositol triphosphate stores indicating that these stores did not contribute to the cytokine response. Sodium Chloride tumor necrosis factor Homo sapiens