Pub. Date : 2001 Jul 20
PMID : 11448162
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | 12-O-tetradecanoylphorbol-13-acetate induces Epstein-Barr virus reactivation via NF-kappaB and AP-1 as regulated by protein kinase C and mitogen-activated protein kinase. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
2 | Electrophoretic mobility shift assays demonstrated that transcription factors NF-kappaB and AP-1 were also activated by TPA in a time-dependent manner. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
3 | These results show that TPA induces EBV reactivation via NF-kappaB and AP-1 and that PKC is an important mediator in regulating gene expression leading to EBV reactivation after TPA treatment of GT38 cells. | Tetradecanoylphorbol Acetate | JunB proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |