Title : Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids.

Pub. Date : 2001 Sep 14

PMID : 11432865






1 Functional Relationships(s)
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1 Two bioactive lysosphingolipids present in HDL particles, sphingosylphosphorylcholine and lysosulfatide, fully mimicked the survival effect of HDL by blocking the mitochondrial pathway of apoptosis and potently activating Akt. psychosine-3'-sulfate ester AKT serine/threonine kinase 1 Homo sapiens