Title : Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin's lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs.

Pub. Date : 2001 Jul 1

PMID : 11431352






1 Functional Relationships(s)
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1 Additionally, piceatannol, an inhibitor of STAT3 activation, down-regulates the expression of Bcl-2. 3,3',4,5'-tetrahydroxystilbene signal transducer and activator of transcription 3 Homo sapiens