Title : Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo.

Pub. Date : 2001 Jul

PMID : 11416024






2 Functional Relationships(s)
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1 Immunoblot analysis of hypothalamic lysates with a phospho-specific STAT3 antibody showed a 6- to 7-fold stimulation of STAT3 tyrosine phosphorylation in response to both leptin and TNFalpha. Tyrosine signal transducer and activator of transcription 3 Rattus norvegicus
2 Immunoblot analysis of hypothalamic lysates with a phospho-specific STAT3 antibody showed a 6- to 7-fold stimulation of STAT3 tyrosine phosphorylation in response to both leptin and TNFalpha. Tyrosine signal transducer and activator of transcription 3 Rattus norvegicus