Pub. Date : 2001 Jul 1
PMID : 11412042
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Atypical PARP cleavage in beta-lap-treated cells was not affected by 100 microM zVAD-fmk; however, coadministration of dicoumarol, a specific inhibitor of NQO1, reduced beta-lap-mediated cytotoxicity, apoptosis, and atypical PARP cleavage in NQO1-expressing cells. | Dicumarol | LAP | Homo sapiens |
| 2 | Atypical PARP cleavage in beta-lap-treated cells was not affected by 100 microM zVAD-fmk; however, coadministration of dicoumarol, a specific inhibitor of NQO1, reduced beta-lap-mediated cytotoxicity, apoptosis, and atypical PARP cleavage in NQO1-expressing cells. | Dicumarol | LAP | Homo sapiens |
| 3 | Dicoumarol increased survival of beta-lap-treated NQO1-expressing LNCaP transfectants. | Dicumarol | LAP | Homo sapiens |