Pub. Date : 2001 Jun 15
PMID : 11406540
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DETA-NONOate (1 mM), which releases NO in the range produced by activated macrophages, induced apoptosis after 36 h in MDA-MB-468 cells via cytochrome c release and caspase-9 and -3 activation. | 2,2'-(hydroxynitrosohydrazono)bis-ethanamine | cytochrome c, somatic | Homo sapiens |
| 2 | FTI (25 microM) potentiated the action of lower concentrations of DETA-NONOate (25-100 microM) by inducing apoptosis in these cells within 24 h by increasing cytochrome c release and caspase-9 and -3 activation. | 2,2'-(hydroxynitrosohydrazono)bis-ethanamine | cytochrome c, somatic | Homo sapiens |