Title : The P2Y11 receptor mediates the ATP-induced maturation of human monocyte-derived dendritic cells.

Pub. Date : 2001 Jun 15

PMID : 11390464






1 Functional Relationships(s)
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1 Recently, it has been shown that ATP and TNF-alpha synergize in the activation and maturation of human dendritic cells (DC); the effect of ATP was reproduced by hydrolysis-resistant derivatives of ATP and was blocked by suramin, suggesting the involvement of a P2 receptor, but the particular subtype involved was not identified. Suramin tumor necrosis factor Homo sapiens