Title : Autoantibody against prothrombin aberrantly alters the proenzyme to facilitate formation of a complex with its physiological inhibitor antithrombin III without thrombin conversion.

Pub. Date : 2001 Jun 15

PMID : 11389017






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The antibody-bound prothrombin formed a stable stoichiometric complex with antithrombin III, consisting of intact prothrombin and an antithrombin III molecule cleaved at the (393)Arg-(394)Ser bond. Arginine serpin family C member 1 Homo sapiens
2 The antibody-bound prothrombin formed a stable stoichiometric complex with antithrombin III, consisting of intact prothrombin and an antithrombin III molecule cleaved at the (393)Arg-(394)Ser bond. Arginine serpin family C member 1 Homo sapiens