Title : Hormonal regulation of tumor suppressor proteins in breast cancer cells.

Pub. Date : 2001 Jan-Mar

PMID : 11384868






2 Functional Relationships(s)
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1 Supplementation of culture medium containing stripped serum with 0.1-1 nM estradiol (E(2)) restored p53 to its level seen in the control within 6-24 h. Under above conditions, treatment of cells with R5020 or RU486 reduced (15-30%) the level of p53. Estradiol tumor protein p53 Homo sapiens
2 Supplementation of culture medium containing stripped serum with 0.1-1 nM estradiol (E(2)) restored p53 to its level seen in the control within 6-24 h. Under above conditions, treatment of cells with R5020 or RU486 reduced (15-30%) the level of p53. Estradiol tumor protein p53 Homo sapiens