Title : Episodic evolution of growth hormone in primates and emergence of the species specificity of human growth hormone receptor.

Pub. Date : 2001 Jun

PMID : 11371582

1 Functional Relationships(s)
Compound Name
Protein Name
1 Also, human growth hormone receptor (GHR) displays species specificity; i.e., it can interact only with human (or rhesus monkey) GH, not with nonprimate GHS: The species specificity of human GHR is largely due to the Leu-->Arg change at position 43, and it has been hypothesized that this change must have been preceded by the His-->Asp change at position 171 of GH. Histidine growth hormone 1 Homo sapiens