Title : Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells.

Pub. Date : 2001 Jul 27

PMID : 11358961






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells. N-Acetylneuraminic Acid sialic acid binding Ig like lectin 10 Homo sapiens
2 When expressed on COS-7 cells, Siglec-10 was able to bind human red blood cells and soluble sialoglycoconjugates in a sialic acid-dependent manner. N-Acetylneuraminic Acid sialic acid binding Ig like lectin 10 Homo sapiens
3 The identification of Siglec-10 as a new Siglec family member and its expression profile, together with its sialic acid-dependent binding capacity, suggest that it may be involved in cell-cell recognition by interacting with sialylated ligands expressed on specific cell populations. N-Acetylneuraminic Acid sialic acid binding Ig like lectin 10 Homo sapiens