Title : Dynamic simulations of 13 TATA variants refine kinetic hypotheses of sequence/activity relationships.

Pub. Date : 2001 May 11

PMID : 11350169






1 Functional Relationships(s)
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1 The factors that combine to produce favorable elements for TBP activity include overall flexibility; minor groove widening, as well as roll, rise, and shift increases at the ends of the TATA element; untwisting within the TATA element accompanied by large roll at the TATA element ends; and relatively low maximal water densities around the DNA. Water TATA-box binding protein Homo sapiens