Title : Role of guanine nucleotides in the regulation of the Ras/cAMP pathway in Saccharomyces cerevisiae.

Pub. Date : 2001 Apr 23

PMID : 11336789






3 Functional Relationships(s)
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Protein Name
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1 The relative amount of Ras2-GTP changes in a parallel way suggesting that there is a correlation with the cytosolic GTP/GDP ratio. Guanosine Diphosphate Ras family GTPase RAS2 Saccharomyces cerevisiae S288C
2 In addition "in vitro" mixed-nucleotide exchange experiments done on purified Ras2 protein demonstrated that the GTP and GDP concentrations influence the extent of Ras2-GTP loading giving further support to their possible regulatory role. Guanosine Diphosphate Ras family GTPase RAS2 Saccharomyces cerevisiae S288C
3 In addition "in vitro" mixed-nucleotide exchange experiments done on purified Ras2 protein demonstrated that the GTP and GDP concentrations influence the extent of Ras2-GTP loading giving further support to their possible regulatory role. Guanosine Diphosphate Ras family GTPase RAS2 Saccharomyces cerevisiae S288C