Title : Inhibition of tissue factor-activated platelets by low-molecular-weight heparins and glycoprotein IIb/IIIa receptor antagonist.

Pub. Date : 2001 Apr 15

PMID : 11323025






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 At 0.01 U/ml, enoxaparin exhibited a stronger inhibition of TF-induced platelet activation compared to ardeparin and dalteparin. Enoxaparin coagulation factor III, tissue factor Homo sapiens
2 Thus, at therapeutic concentrations (0.8-1.2 U/ml), enoxaparin itself was capable of inhibiting TF-mediated activation of platelets to > 70%; whereas tirofiban failed to produce such concentration-dependent inhibition. Enoxaparin coagulation factor III, tissue factor Homo sapiens