Pub. Date : 2001 May
PMID : 11313311
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload. | Iron | solute carrier family 11 member 2 | Homo sapiens |
| 2 | The identification of divalent-metal transporter 1 (DMT1) and ferroportin 1 (FP1) has improved our understanding of transmembrane iron trafficking. | Iron | solute carrier family 11 member 2 | Homo sapiens |
| 3 | The identification of divalent-metal transporter 1 (DMT1) and ferroportin 1 (FP1) has improved our understanding of transmembrane iron trafficking. | Iron | solute carrier family 11 member 2 | Homo sapiens |
| 4 | Moreover, DMT1 and FP1 mRNA levels were significantly increased in patients with iron deficiency, HFE and non-HFE hemochromatosis, whereas they were unchanged in patients with secondary iron overload. | Iron | solute carrier family 11 member 2 | Homo sapiens |
| 5 | In patients with normal iron status or iron deficiency, significant negative correlations between DMT1, FP1 mRNA, and serum iron parameters were found, which were absent in subjects with primary hemochromatosis. | Iron | solute carrier family 11 member 2 | Homo sapiens |
| 6 | CONCLUSIONS: DMT1 and FP1 are centrally involved in iron uptake/transfer in the duodenum and in the adaptive changes of iron homeostasis to iron deficiency and overload. | Iron | solute carrier family 11 member 2 | Homo sapiens |
| 7 | CONCLUSIONS: DMT1 and FP1 are centrally involved in iron uptake/transfer in the duodenum and in the adaptive changes of iron homeostasis to iron deficiency and overload. | Iron | solute carrier family 11 member 2 | Homo sapiens |