Title : Role of tumor necrosis factor on toxicity and cytokine production after isolated hepatic perfusion.

Pub. Date : 2001 Apr

PMID : 11309322






2 Functional Relationships(s)
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1 Serum bilirubin levels were significantly higher (P = 0.017) and platelets lower (P = 0.03) in TNF-treated compared with non-TNF-treated patients. Bilirubin tumor necrosis factor Homo sapiens
2 CONCLUSIONS: Addition of TNF to melphalan during IHP results in significant differences in post-IHP production of IL-6 and IL-8 with associated changes in mean arterial blood pressure and greater regional toxicity, as reflected in higher levels of serum bilirubin. Bilirubin tumor necrosis factor Homo sapiens