Title : The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor.

Pub. Date : 2001 Jun 22

PMID : 11301323






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Disruption of the IFNalpha receptor-RACK1 interaction abolishes not only IFNalpha-induced tyrosine phosphorylation of STAT1 but also activation of STAT2, indicating that RACK1 plays a central role in early signaling through the Jak-STAT pathway. Tyrosine receptor for activated C kinase 1 Homo sapiens
2 Disruption of the IFNalpha receptor-RACK1 interaction abolishes not only IFNalpha-induced tyrosine phosphorylation of STAT1 but also activation of STAT2, indicating that RACK1 plays a central role in early signaling through the Jak-STAT pathway. Tyrosine receptor for activated C kinase 1 Homo sapiens