Title : Site-directed mutagenesis of human nucleoside triphosphate diphosphohydrolase 3: the importance of residues in the apyrase conserved regions.

Pub. Date : 2001 Apr 3

PMID : 11300774






1 Functional Relationships(s)
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Protein Name
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1 Mutagenesis of arginine 146 to proline (R146P) essentially converted the eNTPDase-3 ecto-apyrase to an ecto-ATPase (eNTPDase-2), mainly by decreasing the hydrolysis rates for nucleoside diphosphates. nucleoside diphosphates ectonucleoside triphosphate diphosphohydrolase 3 Homo sapiens