Pub. Date : 2001 Apr 27
PMID : 11297530
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation. | Hydrogen Peroxide | mitogen-activated protein kinase 3 | Mus musculus |
| 2 | Sod2-dependent increases in the steady-state levels of H(2)O(2) led to ERK1/2 activation and subsequent downstream transcriptional increases in matrix metalloproteinase-1 (MMP-1) expression, which were reversed by expression of the H(2)O(2)-detoxifying enzyme, catalase. | Hydrogen Peroxide | mitogen-activated protein kinase 3 | Mus musculus |
| 3 | Sod2-dependent increases in the steady-state levels of H(2)O(2) led to ERK1/2 activation and subsequent downstream transcriptional increases in matrix metalloproteinase-1 (MMP-1) expression, which were reversed by expression of the H(2)O(2)-detoxifying enzyme, catalase. | Hydrogen Peroxide | mitogen-activated protein kinase 3 | Mus musculus |