Title : Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis.

Pub. Date : 2001 Apr 15

PMID : 11281652






1 Functional Relationships(s)
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1 Moreover, Bax translocation, cytochrome c release, and caspase 9 activation were blocked by the broad-spectrum caspase inhibitor, Z-VAD-fmk and the caspase 8-preferential inhibitor, Ac-IETD-CHO, suggesting that the mitochondria might participate in apoptosis by amplifying the upstream death signals. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone cytochrome c, somatic Homo sapiens