Pub. Date : 2001 May
PMID : 11267993
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MED1 acts as a mismatch-specific DNA N-glycosylase active on thymine, uracil, 5-fluorouracil and, weakly, 3,N(4)-ethenocytosine paired with guanine. | Thymine | mediator complex subunit 1 | Homo sapiens |
| 2 | Since G:T mismatches can originate via spontaneous deamination of 5-methylcytosine to thymine, MED1 appears to act as a caretaker of genomic fidelity at CpG sites. | Thymine | mediator complex subunit 1 | Homo sapiens |