Title : Respiratory chain-generated oxidative stress following treatment of leukemic blasts with DNA-damaging agents.

Pub. Date : 2001 Apr 1

PMID : 11262191






1 Functional Relationships(s)
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1 Since glutathione and thioredoxin can protect from drug-induced apoptosis, their upregulation in response to respiratory chain-generated reactive oxygen might represent a cellular adaptation to DNA damage that promotes cell survival. reactive oxygen thioredoxin Homo sapiens