Title : Acute and chronic effects of citalopram on postsynaptic 5-hydroxytryptamine(1A) receptor-mediated feedback: a microdialysis study in the amygdala.

Pub. Date : 2001 Mar

PMID : 11259482






2 Functional Relationships(s)
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1 Local infusion of the 5-HT(1A) receptor agonist flesinoxan (0.3, 1, 3 microM) for 30 min into the amygdala maximally decreased 5-HT to 50% of basal level. flesinoxan 5-hydroxytryptamine receptor 1A Homo sapiens
2 Both the flesinoxan and WAY 100.635 data suggest an involvement of postsynaptic 5-HT(1A) receptor-mediated feedback in the amygdala, which diminishes following chronic citalopram treatment. flesinoxan 5-hydroxytryptamine receptor 1A Homo sapiens