Title : Induction of inducible nitric oxide synthase-NO* by lipoarabinomannan of Mycobacterium tuberculosis is mediated by MEK1-ERK, MKK7-JNK, and NF-kappaB signaling pathways.

Pub. Date : 2001 Apr

PMID : 11254551






2 Functional Relationships(s)
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1 The objective of this investigation was to examine the role of mitogen-activated protein (MAP) kinase (MAPK) and nuclear factor kappaB (NF-kappaB) signaling pathways in the regulation of iNOS and NO* by a mycobacterial cell wall lipoglycan known as mannose-capped lipoarabinomannan (ManLAM). manlam nitric oxide synthase 2, inducible Mus musculus
2 These results indicate that combined IFN-gamma and ManLAM stimulation induced iNOS and NO. manlam nitric oxide synthase 2, inducible Mus musculus