Title : Metastases: the glycan connection.

Pub. Date : 2000

PMID : 11250723






1 Functional Relationships(s)
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1 Associations linking the importance of glycosylation events to tumor biology, especially the progression to metastatic disease, have been noted over many years, Recently, a mouse model in which beta1,6-N-acetylglucosaminyltransferase V (a rate-limiting enzyme in the N-glycan pathway) has been knocked out, was used to demonstrate the importance of glycosylation in tumor progression. n-glycan mannoside acetylglucosaminyltransferase 5 Mus musculus