Title : Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.

Pub. Date : 2001 Mar 13

PMID : 11248092






1 Functional Relationships(s)
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1 In parallel with the enzymatic changes, nrf2-deficient mice had a significantly higher burden of gastric neoplasia after treatment with benzo[a]pyrene than did wild-type mice. Benzo(a)pyrene nuclear factor, erythroid derived 2, like 2 Mus musculus