Title : Induction of epithelial differentiation and DNA demethylation in hamster malignant oral keratinocyte by ornithine decarboxylase antizyme.

Pub. Date : 2001 Jan 4

PMID : 11244502






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ectopic expression of ODC-Az gene in hamster malignant oral keratinocytes led to reduce ODC activity and the subsequent demethylation of 5-methyl cytosines, presumably via the ODC/ polyamines/ decarboxylated S-adenosylmethionine (dc-AdoMet) pathways. Polyamines ornithine decarboxylase, structural 1 Mus musculus
2 Our data suggest that ODC-Az shared the same pathway of polyamines/ dc-AdoMet/DNA methyltransferase (DNA MTase). Polyamines ornithine decarboxylase, structural 1 Mus musculus