Title : Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I.

Pub. Date : 2001 Mar

PMID : 11242114






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Increased de novo ceramide synthesis triggers apoptosis and is associated with massive cell death during neural tube closure, raising the possibility that neural degeneration in HSN1 is due to ceramide-induced apoptotic cell death. Ceramides serine palmitoyltransferase long chain base subunit 1 Homo sapiens
2 Increased de novo ceramide synthesis triggers apoptosis and is associated with massive cell death during neural tube closure, raising the possibility that neural degeneration in HSN1 is due to ceramide-induced apoptotic cell death. Ceramides serine palmitoyltransferase long chain base subunit 1 Homo sapiens